I didn't use a portable version, I used the standard version.
I put on the original post that I did do a complete un-install (cleaned registry and so forth) and reinstall as a final option.
"I tried the only thing I didn't do before and that was to remove it and reinstall it.
During the reinstall I left the 'Defraggler in Explorer' (or similar) option checked - then the right-click menu items were there - but I still had no option to move large files to the end of the drive, and this is the primary reason why I wanted it to work and wanted to use this software."
It worked perfectly and as it should both times, with checking the 'integrate into explorer' and also leaving it unchecked during install. The only thing that this option does is to allow Defraggler to add right-click functionality if to integrate is checked. Saving settings to an ini file does disable this feature - even if selected to when installed, but that is not the issue.
When I say I wanted to move large files to the end of the drive I did not mean during a defrag - that worked fine. I wanted to be able to move large files to the end of the drive by right clicking on them in Explorer and selecting that Defraggler move them. I read somewhere that with Defraggler one could right-click on a large file and move it to the end of the drive from within Explorer - obviously this was not true.
I would like to add that I did install the software properly (with no messing around), as there is no other way to do it as the software will not let an installer mess around.