Sorry for posting on this topic four months after its creation, but I have a similar problem to the one described above. Like LazyCarrot, CCleaner crashes immediately upon launch. Unlike LazyCarrot, I can't remember anything out of the ordinary that I've done recently that might have caused it to start crashing. I did try to use the "Repair Permissions" tool, but canceled after about a minute of nothing happening, realizing that the tool would take more time than I had.
I'm running OSX Version 10.8.2, and trying to run CCleaner Version 1.03.131.
And yes, I've tried restarting my computer (twice), uninstalling/reinstalling CCleaner (twice), and running a virus scan, none of which did anything to help. I've also checked my fonts, all of which are enabled (including Courier New).
I'm at a complete loss as to how to deal with this, so any advice would be appreciated.