While I think CCleaner is a very good product overall, it does seem to have 2 bugs.
Under "Applications" --> "Opera", CCleaner does not seem to know where the Opera 8.5 cache really is located and does not seem to allow reconfiguring to where the cache really is. This may be in part due to the fact that I do not install applications in the "default" location, but rather to a different drive and folder.
I then tried to compensate by using "Options" --> "Custom" --> "Add Folder" and entered the actual cache folder & path. While it shows the folder I indicated in the list, it did not clean out that folder.
Thanks for a great product.