I use iTunes v. 8.1.0.52 (the newest) and CCleaner v. 2.17.853 (I only use iTunes for the iPod and for converting CD's and Wav-files to mp3, otherwise I hate it as well. I'm a big fan of Winamp). iTunes is installed as standard (library files in C:\Documents and Settings\<username>\My Documents\My Music\iTunes\) as is CC (no additional things checked).
After using the cleaner and registry cleaner and starting up iTunes I got the message: Library file is damaged, iTunes will make new file (or something in that general direction) and I got another message twice saying some necessary files got damaged and iTunes needed to be reinstalled.
I don't dare to start CC at the moment to see if it's happening again, because I first wanted to see what you guys where saying.
Next to CC I use the Uniblue registry cleaner, but I already tried that one out and it didn't affect iTunes (for now...) will let you know if the trick "pin to start menu" will help.
Hope that is a little bit more information. When I get the problem again (because I will keep on using CC) I try uploading the screenshot.
Thanks for the quick reply btw.
Tristan