A lot of the suggestions are good, but they seem to be beyond Defraggler's purpose. When I `found' the program, it was billed as a file defrag program. While the suggestions of strategic file placement and background operation would be great, there would be a performance trade off.
For example; I rent movies from an online vendor. They expire every 30 days. If I were to defragment my 500 gig drive with 60+ 1.5 gig movies on, I would kill my system. With Defraggler, I can defrag my system files, my inbox and email folders, everything that matters.
The big fat fragmented wma movie files can be as fragmented as they want to be because they are recycle bin fodder.